Zayyan Sakha as Zaki kecil
Marthino Lio as Amir
I Gusti Ayu Laksmiyani as "Andung", nenek Hamka
Ade Firman Hakim as Karta
Wafda Saifan Lubis as Rozak, suami Kulsum
Roy Sungkono as Rusydi, putra Hamka
Novita Hardini as Fatimah
Yoriko Angeline as Ola
Rey Bong as Hamka kecil
Richard Oh as Tan Beng Kie
Deasy Ratnasari as Umi Safiyah, ibu Hamka
Vino G Bastian as Hamka
Laudya Cynthia Bella as Sitti Raham, istri Hamka
Pritt Timothy as Agus Salim
Mathias Muchus as Sutan Mansur
Teuku Rifnu Wikana as Kariman Amin, paman Hamka
Ajil Ditto as Fahri
Izzati Khansa as Sitti Raham kecil
Alfie Alfandi as Dadang, sipir ketika Hamka di penjara
Reza Rahadian Matulessy as Oemar Said Tjokroaminoto
Mawar Eva De Jongh as Kulsum
Ucok Hasim Batubara as Hamid
Verdi Solaiman as Abdul Karim Oei (Oei Tjeng Hien)
Doni Kusuma as Ayah Kulsum
Donny Damara Prasa Dhana as Haji Rasul, ayah Hamka
Ben Kasyafani as Zainuddin Labai
Ferry Salim as Gubernur Nakashima
Anjasmara as Sukarno
Yoga Pratama as Zaki, putra Hamka
Mellya Baskarani as Aminah
Directing
Fajar Bustomi as Sutradara
Writing & Story Development
Cassandra Massardi as Penulis skenario
Alim Sudio as Penulis skenario
Production
Chand Parwez Servia as Produser
Dewi Soemartojo as Produser pelaksana
Dallas Sinaga as Produser eksekutif
HB Naveen as Produser eksekutif
Frederica as Produser
Sound
Mardi as Perekam suara
Mohamad Ikhsan Sungkar as Penata suara
Cinematography & Camera
Ipung Rachmat Syaiful as Penata kamera
Casting
Nova Sardjono as Pengarah pemilihan pemeran
Gilang Numerouno as Pengarah pemilihan pemeran
Costume & Wardrobe
Samuel Wattimena as Perancang busana
Orlando Bassi as Penata rias prostetik
Jerry Octavianus as Penata rias
Visual Effects
Ganda Hartadi as Efek visual
Editing
Ryan Purwoko as Penata gambar
Music
Purwacaraka as Penata musik
Art & Production Design
Allan Sebastian as Penata artistik